Guest post by Chris Clarke
On Saturday 1st October Dr Chris Clarke and Dr Dada Pisconti from the Institute of Integrative Biology took part in Meet the Scientists at the World Museum Liverpool. The aim of their stand was to convey to the visitors how muscle is made and repaired. There were two activities set up:
1. Two microscopes displaying samples (from their lab) of muscle progenitor cells fixed at the start (day 0) and end (day 3) of a differentiation experiment where individual cells at the start of the experiment fuse into multinucleated muscle fibers, replicating in vivo muscle formation and regeneration. A laptop was also set up showing a time lapse video of the same process.
2. The Muscle Regeneration game. To show guests the process of muscle regeneration in a more hands-on way, a game was set up here children were asked to repair broken Play-doh ‘muscle fibers’ using Play-doh ‘stem cells’. The aim of the game was to split the stem cell in half, turn one half into a new part of a muscle fiber (ie. A sausage) and fix the broken fiber by ‘fusing’ this new fiber with the broken one. 2-3 sets of broken fibers had to be repaired in this way, with children facing off against siblings/friends/parents to finish in the fastest time possible.
They were also assisted on the day by undergraduate students from the University of Liverpool.
Find out more about future events here.