This summer IIB’s Dr Dan Rigden hosted XJTLU student Xiaoyue Song:
Gut bacteria composition and activity can have big effects on human health and disease. There is therefore a lot of interest in understanding proteins and protein families encoded by the principal gut bacteria. Structural genomics has contributing by solving many structures but some of these have been deposited in databases without associated publications fully describing or predicting their functions. Xiaoyou has been focusing on a single family commonly found in gut bacteria, using a range of bioinformatics methods to try to predict its function. She strongly suspects that it is involved in carbohydrate metabolism and is currently trying to pin down the function further.