Science week in Mosspits Lane primary school, 6-7 March 2017

As part of her honours project Mary Roughley visited Mosspits Lane Primary School in Wavertree, Liverpool, during Science week. She has spent an afternoon with each year 6 class and engaged with the pupils on topics such as scales in the universe, the concept and calculation of magnification and the power of using microscopy in biology. As part of her honours project, Mary has planned the session and developed the supporting worksheets and instruction protocols. After a short presentation, the whole class went out onto the playground to collect their own live samples to view under the microscope, the class were then split into three groups to rotate between the three exercises that were organised. The most popular activity was collecting and viewing their samples. The pupils were given magnifying glasses and also had access to the Zeiss stemi labscope to enable them to examine their specimens. They collected insects, worms, leafs, bread crumb, aphids, hairs…They really enjoyed this activity and were fascinated and very excited by what they could see with a microscope: worms digestive tubes, tiny unsuspected hairs on insect legs and “a starry night sky” (salt imaged with transmitted light)!

The pupils also made their own magnifier using water in petri dishes. They learnt how to calculate magnification and used this knowledge to calculate and compare the magnification of a magnifying glass and the magnifier that they made. They realised that their magnifier made with a drop of water was as good as a commercial magnifying glass.

For the third activity, the pupils used the schools computers and an online programme to learn more about scales. The software showed objects of different sizes ranging from galaxies to a proton nucleus. This activity reinforced the idea that microscopes are essentials to biologists, as many things are much too small to be seen with the naked eye. This is what Mary says about her experience: “I received excellent feedback from the pupils. They thoroughly enjoyed the session and some mentioned that they would like to become biologists. They particularly enjoyed using the microscope and collecting their samples and a number of pupils said that the only bad part of the session was packing away! As a proof of the success of the half-day, the teachers had to fight for the children to go out at playtime. They preferred observing their samples under the microscope. I have personally really enjoyed delivering the sessions, I found the experience very rewarding especially when the pupils said they wanted to be biologists! The experience has also made me consider teaching as a career.” This is what the children wrote about the session: “‘I wish the session was longer!!; I liked seeing the intestines in the worm, it was gross but cool!; The bacteria in the pond water was really cool.” It was a very enjoyable experience at all levels: for the children, the teachers, the undergraduate student involved and me, the academic supervisor. Thank you to Mosspits Lane to have worked with us on this project.

Violaine Sée, IIB

Brainiology Event

Brainiology Event

Guest Post : Tom Butts, University of Liverpool

The School of Life Sciences held a ‘making the brain’ workshop in the Liverpool World Museum on Saturday 21st January as part of the ‘Meet the Scientists: Brainiacs’ day. Members of the public (and more to the point, their kids) came along and had a go at a number of activities all designed to get people thinking about the brain, how it works, and how it has evolved.

The first activity was to ‘build a brain’, where people had to assemble a 3D life-size anatomical model of the human brain. The second was ‘evolving the brain’ and involved arranging a number of animal photographs on a large phylogeny (of vertebrates). The final part was to try and match up the pictures of the animals’ brains to the correct animal on the phylogeny as a way to think about how brains have evolved. I had some cracking volunteers, including postdocs, PhD students, Masters’ students, and undergrad students from across the biological diaspora in Liverpool, and it was a cracking day had by all. Though knackering. I now have even vaster levels of respect for primary school teachers.

Speed (dating) Science Careers

On the 19th January, 40 Year 12 students from Life Sciences UTC visited Life Sciences to take part in a Speed Science event with 5 PhD students from IIB.  This was part of their Build My Future Festival.

Small groups of students spent 5 minutes listening to a PhD student talk about their research before being given 5 minutes to ask questions on things such as the PhD student’s research, what university is like? What being a PhD student is like? Which degree programmes the PhD students had taken? before moving to the next PhD student to start the process again. Using this approach the students were able to speak to and ask lots of questions to a 5 different PhD students in a short space of time

The students were really engaged and asking lots of questions, whilst it gave the PhD students chance to practise their science communication.

Thanks to Tushar Piyush, Matthew Agwae, Hammed Badmos, Gospel Nwikue and Jonathan Temple for volunteering to help out at this event

Postcard from Khon Kaen, Thailand – Eddy Spofford and Charlotte Price (MBiolSci students from the Institute of Integrative Biology)

Cholangiocarcinoma (CCA) is more prevalent in Southeast Asian countries compared to the western world, where cases of CCA are rare. Opisthorchis viverrini (OV) infection (opisthorchiasis) is the associated cause of this increase of cases in CCA, and rates of high infection with OV correlate with high CCA occurrence. In the Northeastern Isaan region of Thailand, OV-infection is endemic – this region also suffers high levels of CCA. OV may be transmitted by eating raw or undercooked fish in foods such as such as ‘koi pla’. After consumption, the OV parasite resides in the duodenum, the liver and surrounding bile ducts and can live for up to 20 years. Infection is asymptomatic, making CCA difficult to detect until it presents in its terminal stages. For these reasons, OV is classed as a type 1 carcinogen.

As part of our integrated masters final year project and internship, Charlotte and I are observing the sustained immune response towards OV – one of several contributors to the development of CCA. As part of a Newton Fund project funded by the British Council, we have been conducting our research in the Tropical Disease Research Laboratory (TDRL),  part of Khon Kaen University. So far, we have enjoyed integrating ourselves into a completely new culture and working in a lab with more independence than we have had before. So far it has been an exciting and rewarding experience. TDRL provides a lot of opportunities for international students, so whilst we are submerged in Thai culture we have also been fortunate to meet people from all across the world. This is in addition to making discoveries along the way in the lab. Knowing that our research will contribute towards efforts to reducing OV-infection and CCA mortalities is very humbling.

TDRL developed the “Lawa Model” several years ago and introduced this to Lawa villages 6 years ago. This model aims to educate people about the dangers of OV and eating potentially contaminated fish. Health volunteers are responsible for screening of patients to detect OV and administering praziquantel, as well as other non-OV health issues. They are also required to examine stool samples and educate locals as part of the free education programme in local schools, or ‘door to door’ educating. The health volunteers are key in maintaining the health and awareness of the local communities, whether it be through interpretive dance, adaptations of popular Thai songs or handing out leaflets.

The Lawa Model education programme in schools is free. Before the model was introduced, an average of 10% of children were OV-positive. Now, most schools around the Lawa Region can boast 0% infection. The Model encourages education about OV as part of the school curriculum by rewarding them with certificates. This is promising for future generations that are much less likely to suffer from CCA.

The Lawa Model adopts the ‘EcoHealth’ approach which means a transdisciplinary approach, where experts from different scientific disciplines such as conchology, ichthyology, parasitology, biochemistry and veterinary medicine that target each stage of OV’s lifecycle.  A major failing in previous attempts has been lack of sustained awareness and implementation of control programmes. The Lawa Model has attempted to solve this by encouraging and educating stake holders including local officials, monks, village leaders, schools and the previously mentioned health volunteers who are also responsible for providing regular health checkups for the villagers and checking for OV-infection.

On our visit to Lawa Lake, we saw for ourselves the success of the model, where it was very clear that the majority of people now had a clear understanding of how OV is transmitted. Before the model was introduced six years ago, OV-infection in the human populations in this area was 60%, but this has now fallen to less than 10%. OV-infection in fish has fallen from 70% to <1% and snails infected with OV have dropped to less than 0.2%. As a result of this success, the TDR team are now planning to introduce the Lawa Model into different provinces within Thailand and other neighbouring countries. Charlotte and I recently visited Kalasin, a province nearby to Khon Kaen, which is in very early stages of Lawa Model implementation. It was very eye-opening to see how unaware some people still are in Thailand despite the threat of this disease. However, due to the Lawa Model’s previous success it is likely villages in Kalasin will have the same promising results.

The TDR team from KKU often travels to local Lawa Villages to hold talks about the dangers of OV and explain how it is transmitted. Ultrasound screening is also performed to determine levels of liver complication in patients. Blood samples are also taken from the field and used as part of research about the pathology of OV infection, which precedes CCA. As part of my and Charlotte’s research, we have analysed these blood samples through various immunological assays. Our research will contribute to the current hypothesis that people with a more aggressive immune response are more susceptible to the development of CCA.

The recent ‘National agenda against liver fluke and cancer’ has made clear its aim to remove OV from Thailand in the next 10 years and reduce the number of CCA mortalities. The Lawa Model is a perfect example of how constant attention and support to communities can reduce the infection rate of OV. For this to happen on a national scale, the government must become involved on a permanent level to guarantee replication of the Lawa Model’s success.

After 3 months here, Charlotte and I are continuing to enjoy both the science and the fun that comes with Thai culture. We are fortunate to be part of such a worthwhile project and hope our time here will be beneficial to both ourselves, and the fight against OV and CCA.

Top L-R: Dr Kanin Salao and Eddy processing patient blood samples in the lab; Eddy and Charlotte with Prof Steven Edwards and Dr Helen Wright, who lead the University of Liverpool collaboration with TDRL, and Dr Kanin Salao from TDRL prior to them leaving for Khon Kaen in July; Eddy and Charlotte with other TDRL students paying respects to Prof Banchob Sripa (centre) on “Teachers Day”.

Bottom L-R: Community outreach program in Kalasin; Charlotte carrying out neutrophil isolations in the lab; OV parasite under the microscope.

 

Christmas lectures

Each year we are welcoming students from various secondary schools to our Christmas lectures. This year was once again a success:

Thanks to Jay Hinton (“It’s amazing you’re not dead yet”), Dada Pisconti (“The secret life of stem cells”) and James Hartwell (“Plants to save the world”) for their inspiring talks and thanks to our young visitors for coming.

Earlier version of Jay’s talk:

ENTHUSE – working with teachers

By Luciane V. Mello

One way we can contribute to young people’s enthusiasm for science is by working with their teachers, e.g. through continuing professional development schemes like STEM Insight.

Last February in partnership with the Biochemical Society we received Maria Saeed, from Blackburn College, for her Insight into University experience placement.

maria saeed

Maria Saeed

The week was a great experience and I am now putting into practice what I have learnt. For example, I am working on developing a numeracy skills pack for all learners, and I am hoping to do several practical sessions in the same format I saw at the university that worked very well… I believe the scheme has been invaluable in developing my own teaching practice and the links between the college and Liverpool University in the long-term.

 

I’m delighted to report that Maria Saeed was nominated for the ENTHUSE Further Education Award, an event organised by STEM Learning and the Wellcome Trust to recognise the impact that teachers and technicians have on their pupils, colleagues, schools, colleges and peers.  I would like to thank all members of staff who helped me to offer Maria a wonderful experience during her week in the Department of Biochemistry (IIB) and in the School of Life Sciences: Amal Abdulkadir, Fabia Allen, Peter Alston, Andy Bates, Rob Beynon, Elaine Connor, Caroline Dart, Claire Eyers, Pat Eyers, Karen Fitzsimons, Blair Grubb, Phil Harrison, Keith Hatton, Joscelyn Sarsby, Jerry Turnbull, Susanne Voelkel and Mark Wilkinson.

A successful team work! We are now prepared for other teacher visits so if you are interested, get in touch.

Big Bang NorthWest 2016

The Big Bang North West is a science fair with a variety of companies, stalls and events to excite students from primary school up to sixth form about science, technology, engineering and maths. The Big Bang North West, organised by MerseySTEM, took place last week, Tuesday 5th July, with 5000 students descending upon the fabulous new venue, the Exhibition Centre, Liverpool. This new venue meant all the exhibits were located in one hall with a central stage where various shows would take place, including someone who was screening his bronchoscopy exam! Students from various schools also had the opportunity to present their own scientific projects as part of a National Science and Engineering competition, with quite a varied selection on display.

The School of Life Sciences and the Institute of Integrative Biology were well represented at the event with members taking part in exhibits, judging and moderating.

If you were also exhibiting at the event, please add a comment at the bottom and we will update the page. Thanks!

Institute of Integrative Biology Exhibit

Beth Levick, Gabriel Pedra, Vinnie Keenan

Beth, Gabi and Vinnie ran a game based on a simple SIR (susceptible, infected, recovered) model in the fashion of a Microbe Premier League. Teams battled it out to try and infect the entire population based on random dice rolls in a set time limit. Students loved the game with some returning multiple times to try and beat their friends.

Amy Eacock

Amy took some peppered moths to the exhibit in moth and caterpillar form to discuss her phd work examining how these twig-mimicing caterpillars are able to detect colour and adapt their bodies. Students were really interested in holding the caterpillars although there were screams from some! Amy also had a match the caterpillar to its moth game which went down well with both adults and students.

Lewis White

Lewis brought a selection of animal skulls for students to examine before they tackled his challenging game of placing a number of animals in the correct order on a phylogenetic tree. These included, whales, dolphins, sharks, cats and pandas but it was the primary school children who fared the best!

Rebecca Jones

Becky’s activity involved students and teachers sticking parasites on to the animals they thought those parasites lived in/on. There were some pesky parasites that kept them all guessing though!

Judging and Moderating the NSEC regional heats

Becky and Beth were selected as a judge and moderator for the school projects for the NSEC regional heats.

Victoria Harman

Victoria Harman, STEM Ambassador and member of the Centre for Proteome Research has completed another year as judge in the North West heat of the Big Bang Competition Victoria has been a judge for four years, and has been acting as a head science judge for the last two.

VictoriaH

What’s involved? Judges are allocated a judging partner and about five projects to asses in the morning being given about 20min to speak to each group/individual. The score is based on criteria such as planning, method design, analysis of results, whether the project is the students own idea, and how well it is presented.

There’s quite a lot of pressure on judges – the students have worked so hard over the last academic year on their projects and assessment in just 20 minutes is a big responsibility!

Students dedicate their spare time to produce a project – sometimes individuals, mostly teams. There are juniors, intermediates and seniors categories so there is quite an age span.  As with all competitions there is a range in the standard of projects but every single student or group puts in a lot of hard work. Victoria comments “It’s wonderful to see how proud they are of their work. Some students can be nervous to begin with but in the end they’re all so eager to tell you all about what they have achieved”.

After the morning judging session, the head judges review the scores for the science projects from the morning, and select projects for the shortlist for the nationals. A smaller team of head judges and moderators then meets the students again to review the shortlisted projects before selecting those that will be put forward for the national final. A project is nominated for the Endeavour prize which recognises exceptional hard work, determination and enthusiasm from a student or team.

prize

Victoria says “The Endeavour prize is actually my favorite bit. Considering that science isn’t always about getting the perfect results it’s brilliant to be able to recognize a student or students who have really put their heart and soul into a project”.

If you’d be interested in engaging with the Big Bang Competition, feel free to get in touch with Victoria (vharman@liverpool.ac.uk). She’ll direct you to the right people.

 

Rebecca Jones

I judged the senior category which had some interesting projects ranging from ‘Can mealworms eat plastic?’ to information leaflets on the BRCA gene which could be used in the NHS and online. I also learnt about how environmental issues associated with the Great Barrier Reef can be highlighted to primary school children through an educational toolkit. I also had the privilege of judging and shortlisting for regionals the eventual winners of the Young Scientist of the Year Award from Sandbach High School. Natural Skin Remedies, championed by two girls, had produced and tested a number of different creams to treat eczema. They had carried out a lot of experimental research and presented their work brilliantly. I wish them all the best in the finals next year. Go girls!!

Beth Levick

 I acted as a moderator for the judging, helping to decide which of the teams shortlisted by the main judges would go ahead to the final in March! I met some excellent teams and individuals, with projects ranging from how the length of skis affect your speed, to creating exciting videos of scientific topics using sweets. I was delighted to meet the winner of the “Endeavour” award and discuss her ideas for a greenhouse powered by burning waste. Of the 5 teams that went on to the final I and my partner moderator (also from IIB!) put forward two very clean projects: one on the efficacy of surface cleaners in removing bacteria, and one on commercial bleach products compared to home remedies. The hard work that had gone in to producing some really quality projects was truly inspiring, and all the teams that competed should be proud of the work they put in.

Aquaponics

Jens Thomas

Life Sciences Outreach Society

Juhi Gupta

The University of Liverpool’s Life Sciences Outreach team were back at Big Bang this year. Following last year’s successful workshops, Life Sciences undergraduate students got involved with making sweet DNA models and Breaking Berries in our strawberry DNA extraction workshop! We had a great response from kids and school teachers. And our volunteers had lots of fun too! Thank you to all of the students who helped at the event 🙂

20160705_092909